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Bidhan Dhar

Postdoctoral Research Scholar

Jordan Hall NA

Bio

Using my experience gained from a doctoral program in Italy (University in Camerino) and previous post-doctoral work, I have established a track record in developing and integrating paper/microfluidic systems for cell-based assays and diagnostic tests.  During my doctoral studies, I utilized molecular assays and microarray chip technology (in collaboration with SCIENION AG, Berlin Germany) to analyse DNA and RNA expression and evaluate the quality and portability of complex environmental water samples using fluorescence in situ hybridization (FISH) approach.

Here at North Carolina State University, my focus is to develop a droplet digital PCR assay to detect and quantify mitochondrial DNA.  My earlier postdoc at The University of Central Florida focused on developing point-of-care (POC) compatible diagnostics assays for detection of pathogens and drug susceptibility testing.  I designed and optimized deoxyribozyme (sDz) probes with a colorimetric signal readout for the detection and differentiation of Mycobacterium tuberculosis complex (MTC) and non-tuberculous mycobacteria.  This allowed visual identification of genetic signatures containing drug-resistance point-mutations and optimizing NASBA assay integrating with an in-house made paper chip platform for use in remote locations.

Earlier I was a visiting scholar at the University of Brescia, Italy.  In addition, I held a short-term postdoc at Gachon University, South Korea and focused on developing a paper-based microfluidic devices for on-spot detection of pathogens. I also developed a collaboration between investigators in the London School of Hygiene & Tropical Medicine and Gachon University by preparing an (MRC-KHIDI) UK-Korea partnering awards that was awarded for funding.

My long-term interest is to develop a low-cost, simple POC diagnostics and sensing device for field application of early cancer and diseases diagnostics, drug resistance detection, environmental monitoring and life detection beyond earth.

Publications

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Education

D.V.M., Bangladesh Agricultural University (2003)
Ph.D., Bioscience and Biotechnology, University of Camerino, Italy (2014)